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Trauma-Induced Coagulopathy: Pathophysiology and Treatment Principles

Trauma-induced coagulopathy is not a static laboratory abnormality. It evolves minute by minute alongside hemorrhagic shock, hypothermia, acidosis, dilution and endothelial injury. Professor Denys Surkov connects the coagulation cascade with bedside decisions and explains why a temporarily controlled bleed is not necessarily a solved bleed.

The webinar reframes the timing of Damage Control Resuscitation and Damage Control Surgery, including why the traditional “golden hour” may already be too generous. It examines the limitations of conventional coagulation tests and shows how viscoelastic testing such as ROTEM can help identify problems with fibrinolysis, fibrinogen, platelets and coagulation factors.

The session also compares crystalloids, blood components and whole blood in prehospital and early hospital care, with practical attention to civilian and military trauma logistics in Ukraine. The Q&A moves into calcium replacement during massive hemorrhage, low-titer universal donor blood, transfusion complications, fibrinogen correction and the transition from group O to type-specific blood.

A dense, practice-oriented discussion for learners who want to understand why trauma protocols work, rather than simply memorize another algorithm.

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